分子、细胞与组织小测验x
时间：2020-11-08 12:53:20 来源：勤学考试网 本文已影响 人 
Molecule, Cell and Tissue
Quiz 1 2015.3.11
I. Single-choice Question:
1．The characteristic structure in the 3’ end of eukaryotic mRNA is:
A. poly A
B. “cap” structure?
C. Pribnow box
D. initiation coden
E. termination coden
2. Which of the following amino acid is containing a hydroxyl group?
A. threonine ?
B. lysine
C. cysteine
D. glutamine?
E. glycine
3.Which of the following amino acid is NOT encoded by genetic codon?
A. Glutamine
B. Asparagine ?
C. Phenylalanine
D. Isoleucine?
E. Cystine
4．The major force stabilizes the quaternary structure of hemoglobin is:
A. Hydrogen bond
B. Peptide bond
C. Disulfide bond
D. Hydrophobic interaction
E. Ionic bond
5．Using 70% alcohol before injection will change the bacterium protein by:
A. Denaturation
B. Allosteric regulation
C. Hydrolysis
D. Ionization?
E. Precipitation
6．The completely hydrolysis products of RNA and DNA will include:
A. Same ribose,different bases
B. Same bases, different ribose
C. Different ribose and bases?
D. Different bases ,same ribose
E. None of the above
7.The maximum wavelength of Protein solution is :
A. 260nm
B. 280nm ?
C. 230nm?
D. 240nm
E. 220nm
8. Which of the following element is NOT macro element?
A. Carbon
B. Hydorgen?
C. Nitrogen
D. Phosphorus
E. Oxygen
9. The higher content of which of the following pair of bases will cause higher DNA melting temperature
A. Adenine and Guanine
B. Cytosine and Thymine?
C. Adenine and Thymine
D. Cytosine and Guanine?
E. Adenine and Cytosine? ?
10. Which of the following statement of tRNA is NOT correct?
A.5'end is phosphorylated.
B. tRNA is single strand molecule
C. tRNA contains methylated base
D. Anticoden loop of tRNA is totally same
E. Sequence of 3’ end is -CCA ?
?
II. Please define the following terms:
1.? Amino Acid Residue
?
?2．Nucleotide
?
参考答案：
I． AAEEACBDDD
II． 1. Amino Acid Residue
Except for the amino acid in the two ends, amino acids in a polypeptide chain are all not complete after the formation of peptide bond, so named as amino acid residue.
2. Nucleotide
Small organic molecule and building block of Nucleic acid.it consists of three parts：ribose, phosphate, nitrogenous bases(pyrimidine and purine).
?
?
Quiz 2 2015.3.30
?1. Define the following terms and their relationships to one another: (score 25% )
一、mitotic chromosome
?
二、chromatin
?
三、heterochromatin
?
?
2.? Briefly define what they are and their relationship to each other. (score 15% )
A. Cytosol
?
B. Cytoplasm
?
?
3. Briefly define (one sentence for each) what functions they provide for cells. (score 20% )
A. Mitochondria
?
B. Lysosomes
?
?
C. Golgi apparatus
?
?
4. Which of the following statement is correct? (score 20% ) (Solute指被运输的小分子) D
A. The plasma membrane is highly impermeable to all charged molecules
B. Channels must first bind to solute molecules before they allow them to pass.
C. Transporters allow solutes to cross a membrane at much faster rates than do channels.
D. The plasma membrane of many animal cells contains leaky (always open) K+ channels, yet the K+ concentration in the cytosol is much higher than outside the cell.
E. The membrane potential of an axon temporarily becomes more negative when an action potential excites it.
?
5. Which of the following is not the characteristic of the microfilaments: (score 20% ) D
A. They are comprised of proteins.
B. They can assemble and disassembly frequently.
C. They participate in cell division.
D. Actin that comprises of microfilaments varies in epithelial cells and neural cells.
?
Quiz for "Electrical Activity Of Cells"(2015-05-25)
I. Explain the following term
1. Depolarization去极化
2. Saltatory conduction跳跃式传导
?
? 3. Isometric contraction等长收缩
?
II. Single choice questions
? 1. How would the resting membrane potential change when extracellular potassium concentration rises from 4 mM to 5 mM?
√A. RP will be more depolarized;
B. RP will be hyperpolarized；
C. No change；
D. Cell will fire action potential
?
? 2．Which of the following statements about chemically-gated ion channels is false？
? A. Certain chemical transmitters can cause the channels to open；
? B. They are membrane proteins with important functions;
C. The acetylcholine receptor in end-plates of skeletal muscles is a typical chemically-gated ion channel；
? √D. The acetylcholine receptors of smooth muscles are chemically-gated ion channels.
?
? 3. The rising phase (phase 0) of the action potential of cardiac myocytes is due to:
? √A．The opening of voltage-gated sodium channels；
?B．The closure of voltage-gated sodium channels；
?C．The opening of voltage-gated potassium channels；
?D．The closure of voltage-gated potassium channels.
?
? 4．Botulinum toxin causes paralysis of skeletal muscles by:
? A. Blocking voltage-gated sodium channels and hence the propagation of action potentials；
√B. Blocking acetylcholine release from motor neurons;
?C. Blocking acetylcholine receptors at the end plates；
? D. Blocking choline esterase in the cleft of the neuromuscular junction.
?
? 5. Insulin secretion by the beta cells:
? A. is independent of ion channel regulation;
?B. is independent of neural regulation;
? C. is stimulated by activation of the voltage-gated sodium channels;
? √D. is inhibited by the activity of ATP-dependent potassium channels.
?
Team-Based Learning (TBL) 2015.6.1
1. 小明给实验小鼠使用了某种药物后，发现小鼠肌肉组织细胞之间缝隙变大，你认为该药物可能导致肌肉细胞：E
A.钙黏素基因表达减少 B.转运到细胞膜上的钙黏素减少
C.与钙黏素结合的锚定蛋白减少? D.细胞间隙中的钙离子减少
E.以上都有可能
2. 以下说法正确的是：E
A.细胞骨架的参与使间隙连接结构更加牢固。
B.胶原比透明质酸吸水性好，所以要想使皮肤水嫩补充胶原更重要。
C.上皮组织与结缔组织中的细胞外基质的成分与功能都是相同的。
D.EMT（ Epithelial-Mesenchymal Transition ）现象只出现在肿瘤形成和发展过程中。
E.上皮组织中细胞连接结构比肌肉组织中丰富。
3. 以下说法正确的是：D
A.生长因子能够通过血液运输到达效应组织，促进靶细胞增殖。
B.每种信号都有各自独特的信号转导通路。
C.“分子开关”就是指G蛋白。
D.乙酰胆碱在不同类型的细胞上有不同的受体，既有G蛋白偶联受体，又有离子通道受体。
E.小分子信使能够迅速传递信号的原因就是因为其分子小。
4. 生长因子能够：C
A.与G蛋白偶联受体结合 B.与核受体结合，激活基因转录。
C.与酶偶联受体结合，并使之发生二聚化。 D.使基因调控蛋白水解
E.在短期内促进大量细胞内信使分子cAMP生成
5. 形成有功能的胰岛素过程中有几种细胞结构的参与，以下哪种结构是不需要的：E
A.高尔基体 B.内质网 C.微管
D.核糖体? E.溶酶体
6. 小明在细胞的培养液中加入抑制网格蛋白功能的药物，他可能会观察到：E
A.细胞内溶酶体数目增多? B.溶酶体内酸性程度增加
C.细胞内自噬体增加 D.能在培养液里检测到更多的网格蛋白
E.细胞内吞减少
7. 以下哪一项是不正确的：B
A. 微管蛋白的异二聚体发生聚合和组装形成微管结构-包括细胞质微管和纺锤体微管。
B. 中心体、基体、纤毛、鞭毛和微绒毛的化学成分中都有α-和β-tubulin。
C. 如果没有肌动蛋白，细胞在有丝分裂时可以形成纺锤体并拉动染色体分离，但是不能一分为二。
D. 阻止微管或微丝解聚的化合物可以造成细胞增殖障碍，因而可以成为抗癌药。
E. 动粒是细胞增殖过程中出现的连接染色体与纺锤体微管的结构。
8. 下列关于细胞周期的叙述，正确的是：C
A．用蛋白质合成抑制剂处理G1期细胞，不影响其进入S期。
B．S期细胞的染色体数目已增加一倍。
C．G2期细胞的DNA含量已增加一倍。
D．用紫杉醇处理细胞群体，M期细胞的比例会减少。
E. ?Cdk的活性不受生长因子影响。
